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Research and Breast Cancer

Research and Breast Cancer

Research and Breast Cancer There are many unanswered questions about the nature, behaviour and treatment of breast cancer. Some insights can be gained from statistical study of the responses to treatments of large numbers of patients over many years. Data Sets The Southampton University Hospitals Breast Surgical Unit has maintained a database for all patients treated with the disease for some twenty years, and this has been computerised for the past six years. This database allows us to conduct a variety of retrospective studies and to measure outcomes. Some of these studies are undertaken as original studies by Fourth Year Medical Students as part of their training The advances in computer and software technology allow large and complex data sets to be studied in new and more informative ways. We are seeking to devise and apply new systems which will give us better insights into the interactions and benefits of multiple treatment interventions over the course of the disease. Laboratory Research In order for us to understand the biology of cancer cells, and in particular the nature and reasons for treatment failure, some work must be conducted in laboratories, using cell lines and human tissue. We work closely with staff of the Southampton University Cancer Sciences Division and with other Academic Units, in supporting original research by surgeons in training and by PhD students. We have recently completed two PhD studentships in conjunction with colleagues at the University of Leicester into mechanisms of drug resistance in human cell lines. Funding of Research Cancer Research is largely funded by charitable donations and bequests. Some support comes from Local and National Charities, and by award making bodies such as the Royal College of Surgeons of England. There is a charitable fund to support research within the Southampton Breast and Endocrine Unit. Enquiries about donations can be directed to the Southampton University Hospitals Fund Administrator, Mr Ken Amy, at the Hospital Management Offices (direct line tel 02380 798588). Text provided by Mr David Rew, Copyright 2009


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